Could omicron subvariant BQ.1.1 render COVID drugs useless?

A health worker administers a dose of COVID-19 vaccine during a vaccination clinic in Reading, Pa.

A well being employee administers a dose of COVID-19 vaccine throughout a vaccination clinic in Studying, Pa.

Matt Rourke, Related Press

The omicron variant of COVID-19 continues to be evolving, and new omicron subvariants have a greater capacity to evade coronavirus medication or immunity acquired by way of previous an infection or vaccination.

The record of variants which may be a trigger for concern is barely rising. Subvariant BQ.1.1, an offspring of the BA.5, could possibly evade all protection instruments we've got in opposition to COVID-19, resulting in extra hospitalizations and extra instances of lengthy COVID and demise.

What's BQ.1.1?

Subvariants BA.5 and BA.4.6 make up a lot of the reported instances within the U.S., based on Facilities for Illness Management and Prevention estimates.

However, as Salon reported, this might change within the coming weeks as BA.5’s newer mutations unfold in Europe.

Cornelius Roemer, a viral evolution professional on the College of Basel, mentioned that BQ.1.1 is spreading quickly.

“It's turning into fairly clear that BQ.1.1 will drive a variant wave in Europe and North America earlier than the top of November,” he mentioned in a tweet. “Its relative share has saved greater than doubling each week.”

How do mutations work?

Most of the omicron lineages have related mutations and this “sample means that these mutations confer an evolutionary benefit, one that might enable the virus to proceed to unfold amongst individuals who have completely different layers of safety, from vaccination and infections from earlier Omicron lineages,” as Andrew Joseph wrote for well being information website Stat.

Andy Pekosz, a microbiology professor at Johns Hopkins Bloomberg Faculty of Public Well being, instructed International Information that the BQ.1.1, which was found a couple of weeks in the past, has “essentially the most capacity to flee vaccine-induced immunity, in addition to some antibody therapies,” at the very least on paper.

“In order that’s one of many explanation why we’re focusing in on this one and making an attempt to maintain monitor of what it’s doing and the place it's.”

How are you going to shield your self?

Sure, the virus will always mutate, however total, nations are higher outfitted to cope with COVID-19 after utilizing varied measures to forestall infections.

“I do know there’s no mandates round nowadays, however you possibly can decrease your particular person threat of getting COVID by placing on a masks in an indoor setting the place we all know the overwhelming majority of COVID is transmitted,” mentioned Dr. Isaac Bogoch, an infectious ailments specialist with the College Well being Community in Toronto, per International Information.

Vaccines, testing and anti-viral therapies nonetheless work in opposition to the BA.5. As Hanna Seariac reported, the Commonwealth Fund estimates that “if 80% of eligible folks get their COVID-19 booster by Dec. 31, then almost 90,000 lives may very well be saved.”

What are the highest omicron signs to look out for?

As I beforehand reported, omicron subvariants have a shorter incubation interval, which is why the signs might seem earlier. The worst symptom is a “throat on hearth,” mentioned UCSF’s Dr. Peter Chin-Hong.

Essentially the most widespread omicron-related signs are:

  • Cough.
  • Fatigue.
  • Congestion.
  • Runny nostril.

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